牛津:血清素改變了人們學(xué)習(xí)和應(yīng)對(duì)負(fù)面信息的方式
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2024-09-18 15:29:11
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<div class="field field-name-field-body field-type-text-with-summary field-label-hidden" style="margin: 0px 0px 2em; padding: 0px; border-width: 0px; font-stretch: inherit; font-size: 1.125em; line-height: 1.5em; font-family: 'PT Serif', Georgia, 'Times New Roman', serif; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px; background-color: #ffffff; color: #2c2c2c; white-space: normal;">
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><img style="display: block; margin-left: auto; margin-right: auto;" src="https://info.compassedu.hk/sucai/content/1728285741247/1728285741247.png" width="654" height="323" /></p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;">牛津大學(xué)<a style="margin: 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-style: none; text-decoration-line: none; color: #2f72a8;" href="https://www.psych.ox.ac.uk/">精神病學(xué)系</a>和國(guó)家健康與護(hù)理研究所 (NIHR) <a style="margin: 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-style: none; text-decoration-line: none; color: #2f72a8;" href="https://oxfordhealthbrc.nihr.ac.uk/">牛津健康生物醫(yī)學(xué)研究中心 (OH BRC)</a> 的科學(xué)家們的研究發(fā)現(xiàn),血清素水平升高的人對(duì)懲罰性結(jié)果(例如,在游戲中輸錢(qián))的敏感性降低,而不會(huì)顯著影響對(duì)獎(jiǎng)勵(lì)結(jié)果(贏錢(qián))的敏感性。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br />他們發(fā)現(xiàn),增加血清素使個(gè)人能夠更好地控制自己的行為,尤其是在接觸負(fù)面信息時(shí)。該研究還表明,血清素水平升高有益于不同類(lèi)型的記憶。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br /><br />該論文的主要作者、牛津大學(xué)精神病學(xué)系的<a style="margin: 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-style: none; text-decoration-line: none; color: #2f72a8;" href="https://www.psych.ox.ac.uk/team/michael-colwell">邁克爾·科爾威爾(Michael Colwell</a>)說(shuō):“這些發(fā)現(xiàn)為血清素如何影響人類(lèi)行為提供了新的視角,尤其是在負(fù)面環(huán)境中。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br />“我們相信它可能會(huì)為抑郁癥的病因和治療提供重要的見(jiàn)解。”</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br /><br />研究人員沒(méi)有使用傳統(tǒng)的抗抑郁藥(SSRI 或選擇性血清素再攝取抑制劑)來(lái)測(cè)試反應(yīng),而是使用一種新技術(shù)來(lái)測(cè)試血清素的作用,使用選擇性血清素釋放劑,這種藥物目前用于治療一種罕見(jiàn)的癲癇形式稱(chēng)為 Dravet 綜合征。與傳統(tǒng)技術(shù)不同,這種新藥直接增加人腦中的血清素水平。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br />牛津大學(xué)認(rèn)知神經(jīng)科學(xué)教授、OH BRC 抑郁癥治療學(xué)主題負(fù)責(zé)人 <a style="margin: 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-style: none; text-decoration-line: none; color: #2f72a8;" href="https://www.psych.ox.ac.uk/team/catherine-harmer">Catherine Harmer 教授</a>說(shuō):“盡管進(jìn)行了近一個(gè)世紀(jì)的研究,但我們對(duì)血清素如何影響人類(lèi)行為的理解仍然不清楚且存在爭(zhēng)議。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br /><br />“這為我們提供了一些關(guān)于血清素在人類(lèi)中的作用的令人興奮的新信息。它表明,與抑郁癥和抗抑郁藥的作用有關(guān)的血清素在處理消極事物方面的作用更大,而不是促進(jìn)積極反應(yīng)。血清素通常被俗稱(chēng)為 “快樂(lè)的化學(xué)物質(zhì)”,但也許現(xiàn)在是我們將其視為 “不那么糟糕的化學(xué)物質(zhì) ”的時(shí)候了。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br />牛津大學(xué)副教授 <a style="margin: 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-style: none; text-decoration-line: none; color: #2f72a8;" href="https://www.psych.ox.ac.uk/team/susannah-murphy">Susannah Murphy 教授</a>說(shuō):“通過(guò)直接操縱大腦中血清素的水平,這項(xiàng)研究幫助我們了解這種重要的大腦化學(xué)物質(zhì)在人類(lèi)中發(fā)揮的一些核心功能。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br />“我們的研究結(jié)果強(qiáng)調(diào)了血清素在努力的認(rèn)知過(guò)程中發(fā)揮的核心作用,例如我們阻止不受歡迎的行為的能力。這項(xiàng)研究有助于進(jìn)一步理解為什么改變血清素水平的藥物是治療許多精神疾病的有效方法,包括抑郁癥、焦慮癥和強(qiáng)迫癥。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br /><br />該研究涉及 26 名參與者,他們接受了增加血清素的藥物,另有 27 名參與者在對(duì)照組中,他們被要求完成一系列測(cè)量學(xué)習(xí)和行為控制的任務(wù)。然后使用最先進(jìn)的模型來(lái)了解參與者的行為。</p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"> </p>
<p style="margin: 0px 126.757px 1em 0px; padding: 0px; border-width: 0px; font-style: inherit; font-weight: inherit; font-stretch: inherit; font-size: 18px; line-height: inherit; font-family: inherit; font-optical-sizing: inherit; font-size-adjust: inherit; font-kerning: inherit; font-feature-settings: inherit; font-variation-settings: inherit; vertical-align: baseline; outline-width: 0px;"><br /><span style="font-family: 'Tahoma For Number', 'Chinese Quote', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei', 'Helvetica Neue', Helvetica, Arial, sans-serif; color: #000000; font-size: 14px;">論文“</span><span style="font-family: 'Tahoma For Number', 'Chinese Quote', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei', 'Helvetica Neue', Helvetica, Arial, sans-serif; color: #000000; font-size: 14px; font-style: inherit; font-weight: inherit;">人類(lèi)直接釋放血清素塑造厭惡學(xué)習(xí)和抑制</span><span style="font-family: 'Tahoma For Number', 'Chinese Quote', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei', 'Helvetica Neue', Helvetica, Arial, sans-serif; color: #000000; font-size: 14px; font-style: inherit; font-weight: inherit;">”發(fā)表在</span><span style="font-family: 'Tahoma For Number', 'Chinese Quote', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei', 'Helvetica Neue', Helvetica, Arial, sans-serif; color: #000000; font-size: 14px; font-style: inherit; font-weight: inherit;">《自然通訊》</span><span style="font-family: 'Tahoma For Number', 'Chinese Quote', -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'PingFang SC', 'Hiragino Sans GB', 'Microsoft YaHei', 'Helvetica Neue', Helvetica, Arial, sans-serif; color: #000000; font-size: 14px; font-style: inherit; font-weight: inherit;">上。</span></p>
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